References

Project Leaflet References

Baldwin, C. Y., & Woodard, C. J. (2009). The architecture of platforms: A unified view A. Gawer (Ed.) Platforms, markets and innovation (pp. 19-44).

Cornford, T., & Lichtner, V. (2014). Digital Drugs: An anatomy of new medicines. In B. Doolin, E. Lamprou, N. Mitev, & L. McLeod (Eds.), Information Systems and Global Assemblages: (Re)Configuring Actors, Artefacts, Organizations. Berlin Heidelberg: Springer-Verlag

Kallinikos, J., Aaltonen, A., & Marton, A. (2013). The ambivalent ontology of digital artefacts. MISQ, 37(2), 357-370.

Magretta, J. (2002). Why business models matter. Harvard Business Review, 80(5), 86.

Yoo, Y. (2012). Digital Materiality and the Emergence of an Evolutionary Science of the Artificial. In P. Leonardi, B. Nardi, & J. Kallinikos (Eds.), Materiality and Organizing: Social Interaction in a Technological World (pp. 134-154). Oxford: Oxford University Press.

Project Outputs

Cornford, T., & Lichtner, V. (2014). Digital Drugs: An anatomy of new medicines. In B. Doolin, E. Lamprou, N. Mitev, & L. McLeod (Eds.), Information Systems and Global Assemblages: (Re)Configuring Actors, Artefacts, Organizations. Berlin Heidelberg: Springer-Verlag

D3 project. (2015). D3: DELIVERING DIGITAL DRUGS project leaflet (1 ed.). London: London School of Economics and Political Science.

D3 project. (2015). Following Digital Drugs  (poster): London School of Economics and Political Science.

 

Project Members Writings

Cornford, T., & Lichtner, V. (2014). Digital Drugs: An anatomy of new medicines. In B. Doolin, E. Lamprou, N. Mitev, & L. McLeod (Eds.), Information Systems and Global Assemblages: (Re)Configuring Actors, Artefacts, Organizations. Berlin Heidelberg: Springer-Verlag

Cornford, T., Savage, I., Jani, Y., Franklin, B. D., Barber, N., Slee, A., & Jacklin, A. (2009). Learning lessons from electronic prescribing implementations in secondary care. Studies in health technology and informatics, 160(Pt 1), 233-237.

Klecun, E., Lichtner, V., Cornford, T., & Petrakaki, D. (2014). Evaluation as a Multi-Ontological Endeavour: A Case from the English National Program for IT in Healthcare. Journal of the Association for Information Systems, 15(3), 147-176.

Lichtner, V., Cornford, T., & Klecun, E. (2013). Clinical Computer Systems Survey (CLICS): Learning about Health Information Technology (HIT) in its Context of Use. Medinfo 2013: Proceedings of the 14th World Congress on Medical and Health Informatics, Pts 1 and 2, 192, 422-426. doi: Doi 10.3233/978-1-61499-289-9-422

Lichtner, V., Venters, W., Hibberd, R., Cornford, T., & Barber, N. (2013). The fungibility of time in claims of efficiency: The case of making transmission of prescriptions electronic in English general practice. International Journal of Medical Informatics, 82(12), 1152-1170. doi: DOI 10.1016/j.ijmedinf.2013.08.001

Petrakaki, D., Cornford, T., Hibberd, R., Lichtner, V., & Barber, N. (2011). The Role of Technology in Shaping the Professional Future of Community Pharmacists: The Case of the Electronic Prescription Service in the English National Health Service. Researching the Future in Information Systems, 356, 179-195.

Robertson, A., Cresswell, K., Takian, A., Petrakaki, D., Crowe, S., Cornford, T., . . . Sheikh, A. (2010). Implementation and adoption of nationwide electronic health records in secondary care in England: qualitative analysis of interim results from a prospective national evaluation. British Medical Journal, 341. doi: Artn C4564 Doi 10.1136/Bmj.C4564

Sheikh, A., Cornford, T., Barber, N., Avery, A., Takian, A., Lichtner, V., . . . Cresswell, K. (2011). Implementation and adoption of nationwide electronic health records in secondary care in England: final qualitative results from prospective national evaluation in “early adopter” hospitals. British Medical Journal, 343. doi: Artn D6054 Doi 10.1136/Bmj.D6054

Takian, A., Petrakaki, D., Cornford, T., Sheikh, A., & Barber, N. (2012). Building a house on shifting sand: methodological considerations when evaluating the implementation and adoption of national electronic health record systems. BMC health services research, 12(1), 105.

 

Full project bibliography

Annas, G. J., & Sherman, E. (1999). Thalidomide and the Titanic: Reconstructing the Technology Tragedies of the Twentieth Century. Health Law and Ethics, 89(1), 98–101.

Baldwin, C. Y., & Woodard, C. J. (2009). The architecture of platforms: A unified view A. Gawer (Ed.) Platforms, markets and innovation (pp. 19-44).

Beaulieu, A. (2001). Voxels in the Brain Neuroscience, Informatics and Changing Notions of Objectivity. Social Studies of Science, 31(5), 635-680.

Beaulieu, A. (2004). From brainbank to database: the informational turn in the study of the brain. Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences, 35(2), 367-390.

Bell, G. C., Crews, K. R., Wilkinson, M. R., Haidar, C. E., Hicks, J. K., Baker, D. K., . . . Hoffman, J. M. (2014). Development and use of active clinical decision support for preemptive pharmacogenomics. Journal of the American Medical Informatics Association, 21(e1), e93-e99. doi: 10.1136/amiajnl-2013-001993

Benkler, Y. (2006). The wealth of networks: How social production transforms markets and freedom. New Haven: Yale University Press.

Bhattacharya, S. (2005). Up to 140,000 heart attacks linked to Vioxx.   Retrieved 11 September 2014, from http://www.newscientist.com/article/dn6918-up-to-140000-heart-attacks-linked-to-vioxx.html#.VBGLgGMvDTd

Blumenthal, D. (2013). A Tale of Two Angels. Annals of Internal Medicine, 158(6), 489-490. doi: 10.7326/0003-4819-158-6-201303190-00596

Blumenthal, D., & Tavenner, M. (2010). The “Meaningful Use” Regulation for Electronic Health Records. New England Journal of Medicine, 363(6), 501-504. doi: doi:10.1056/NEJMp1006114

Brynjolfsson, E. (2011). Wired for innovation: how information technology is reshaping the economy. MIT Press Books, 1.

Buntin, M. B., Jain, S. H., & Blumenthal, D. (2010). Health Information Technology: Laying The Infrastructure For National Health Reform. Health Affairs, 29(6), 1214-1219. doi: 10.1377/hlthaff.2010.0503

Burch, D. (2010). Taking the Medicine: A Short History of Medicine’s Beautiful Idea, and our Difficulty Swallowing It. London: Vintage.

Burstin, H. (2013). The Journey to Electronic Performance Measurement. Annals of Internal Medicine, 158(2), 131-132. doi: 10.7326/0003-4819-158-2-201301150-00009

Chatellier, G., Zapletal, E., Lemaitre, D., Menard, J., & Degoulet, P. (1996). The number needed to treat: a clinically useful nomogram in its proper context. BMJ: British Medical Journal, 312(7028), 426.

Chen, R., Mias, George I., Li-Pook-Than, J., Jiang, L., Lam, Hugo Y. K., Chen, R., . . . Snyder, M. (2012). Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes. Cell, 148(6), 1293-1307. doi: http://dx.doi.org/10.1016/j.cell.2012.02.009

Claxton, K., Briggs, A., Buxton, M. J., Culyer, A. J., McCabe, C., Walker, S., & Sculpher, M. J. (2008). Value based pricing for NHS drugs: an opportunity not to be missed? BMJ: British Medical Journal, 336(7638), 251.

Claxton, K., Sculpher, M., & Carroll, S. (2011). Value-based pricing for pharmaceuticals: its role, specification and prospects in a newly devolved NHS [Centre for Health Economics Research Paper 60]. York: University of York.

Connolly, K. (2010). Can ‘digital drugs’ get you high?   Retrieved 26 June 2014, from http://www.bbc.co.uk/news/world-us-canada-10668480

Cornford, T., & Lichtner, V. (2014). Digital Drugs: An anatomy of new medicines. In B. Doolin, E. Lamprou, N. Mitev, & L. McLeod (Eds.), Information Systems and Global Assemblages: (Re)Configuring Actors, Artefacts, Organizations. Berlin Heidelberg: Springer-Verlag

Cornford, T., Savage, I., Jani, Y., Franklin, B. D., Barber, N., Slee, A., & Jacklin, A. (2009). Learning lessons from electronic prescribing implementations in secondary care. Studies in health technology and informatics, 160(Pt 1), 233-237.

De Landa, M. (2002). Intensive Science and Virtual Philosophy. London: Continuum Press.

Dixon, B. E., Jabour, A. M., Phillips, E. O. K., & Marrero, D. G. (2014). An informatics approach to medication adherence assessment and improvement using clinical, billing, and patient-entered data. Journal of the American Medical Informatics Association, 21(3), 517-521. doi: 10.1136/amiajnl-2013-001959

Doganova, L., & Eyquem-Renault, M. (2009). What do business models do?: Innovation devices in technology entrepreneurship. Research Policy, 38(10), 1559-1570.

FDA. (2013). Paving the Way for Personalized Medicine – FDA’s Role in a New Era of Medical Product Development: U.S. Department of Health and Human Services, U.S. Food and Drug Administration.

FDA. (2014). The Drug Development Process.   Retrieved 11 September 2014, from http://patientnetwork.fda.gov/learn-how-drugs-devices-get-approved/drug-development-process

Freifeld, C., Brownstein, J., Menone, C., Bao, W., Filice, R., Kass-Hout, T., & Dasgupta, N. (2014). Digital Drug Safety Surveillance: Monitoring Pharmaceutical Products in Twitter. Drug Safety, 37(5), 343-350. doi: 10.1007/s40264-014-0155-x

Gitelman, L. (Ed.). (2013). Raw data is an oxymoron: MIT Press.

Goldspiel, B. R., Flegel, W. A., DiPatrizio, G., Sissung, T., Adams, S. D., Penzak, S. R., . . . McKeeby, J. W. (2014). Integrating pharmacogenetic information and clinical decision support into the electronic health record. Journal of the American Medical Informatics Association, 21(3), 522-528. doi: 10.1136/amiajnl-2013-001873

Goozner, M. (2004). The $800 Million Pill – The Truth behind the Cost of New Drugs. Berkley and Los Angeles, USA: University of California Press.

Hamburg, M. A., & Collins, F. S. (2010). The Path to Personalized Medicine. New England Journal of Medicine, 363(4), 301-304. doi: doi:10.1056/NEJMp1006304

Hawe, P., Shiell, A., & Riley, T. (2004). Complex interventions: how “out of control” can a randomised controlled trial be? Bmj, 328(7455), 1561-1563. doi: 10.1136/bmj.328.7455.1561

Henfridsson, O., & Bygstad, B. (2013). The generative mechanisms of digital infrastructure evolution. MIS quarterly, 37(3), 907-931.

Hilda, B. (2006). Down and almost out in Scotland: George Orwell, tuberculosis and getting streptomycin in 1948. J R Soc Med, 99(2), 95-98. doi: 10.1258/jrsm.99.2.95

Hingorani, A. D., Windt, D. A. v. d., Riley, R. D., Abrams, K., Moons, K. G. M., Steyerberg, E. W., . . . Hemingway, H. (2013). Prognosis research strategy (PROGRESS) 4: Stratified medicine research. Bmj, 346. doi: 10.1136/bmj.e5793

Howard, A., Magretta, J., & Sawhill, J. (1995). Surviving Success – an Interview with the Nature Conservancys Sawhill,John. Harvard Business Review, 73(5), 109-118.

Jacobides, M. G., & Winter, S. G. (2012). Capabilities: Structure, agency, and evolution. Organization Science, 23(5), 1365-1381.

Kallinikos, J. (2011). Governing through technology: Information artefacts and social practice: Palgrave Macmillan.

Kallinikos, J., Aaltonen, A., & Marton, A. (2013). The ambivalent ontology of digital artefacts. MISQ, 37(2), 357-370.

Kawamoto, K., Lobach, D., Willard, H., & Ginsburg, G. (2009). A national clinical decision support infrastructure to enable the widespread and consistent practice of genomic and personalized medicine. BMC Medical Informatics and Decision Making, 9(1), 17.

Kessler, R., & Glasgow, R. E. (2011). A Proposal to Speed Translation of Healthcare Research Into Practice: Dramatic Change Is Needed. American Journal of Preventive Medicine, 40(6), 637-644. doi: http://dx.doi.org/10.1016/j.amepre.2011.02.023

Klecun, E., Lichtner, V., Cornford, T., & Petrakaki, D. (2014). Evaluation as a Multi-Ontological Endeavour: A Case from the English National Program for IT in Healthcare. Journal of the Association for Information Systems, 15(3), 147-176.

Leonardi, P. M. (2010). Digital materiality? How artifacts without matter, matter. First Monday, 15(6).

Lesko, L. J., Zineh, I., & Huang, S. M. (2010). What Is Clinical Utility and Why Should We Care? Clin Pharmacol Ther, 88(6), 729-733.

Lewis, J., Lipworth, W., & Kerridge, I. (2014). Ethics, Evidence and Economics in the Pursuit of “Personalized Medicine”. Journal of Personalized Medicine, 4(2), 137-146.

Lichtner, V., Cornford, T., & Klecun, E. (2013). Clinical Computer Systems Survey (CLICS): Learning about Health Information Technology (HIT) in its Context of Use. Medinfo 2013: Proceedings of the 14th World Congress on Medical and Health Informatics, Pts 1 and 2, 192, 422-426. doi: Doi 10.3233/978-1-61499-289-9-422

Lichtner, V., Venters, W., Hibberd, R., Cornford, T., & Barber, N. (2013). The fungibility of time in claims of efficiency: The case of making transmission of prescriptions electronic in English general practice. International Journal of Medical Informatics, 82(12), 1152-1170. doi: DOI 10.1016/j.ijmedinf.2013.08.001

Lichtner, V and Venters, W. (2011) Journey to DOR: a retro science-fiction story on researching eprescribing. In: Chiasson, M., Henfridsson, O., Karsten, H. and DeGross, J. I., (eds.) Researching the future in information systems. IFIP Advances in Information and Communication Technology (356). Springer, pp. 151-161;

Liu, J. L., & Wyatt, J. C. (2011). The case for randomized controlled trials to assess the impact of clinical information systems. Journal of the American Medical Informatics Association, 18(2), 173-180.

Magretta, J. (2002). Why business models matter. Harvard Business Review, 80(5), 86.

Marcus, G. E., & Saka, E. (2006). Assemblage. Theory, Culture & Society, 23(2-3), 101-106. doi: 10.1177/0263276406062573

Merlin, T., Farah, C., Schubert, C., Mitchell, A., Hiller, J. E., & Ryan, P. (2013). Assessing Personalized Medicines in Australia: A National Framework for Reviewing Codependent Technologies. Medical Decision Making, 33(3), 333-342. doi: 10.1177/0272989×12452341

MHRA. (2013). Pharmacovigilance – how we monitor the safety of medicines, Medicines and Healthcare Products Regulatory Agency.   Retrieved 26 June 2014, from http://www.mhra.gov.uk/Safetyinformation/Howwemonitorthesafetyofproducts/Medicines/Pharmacovigilance/index.htm

Mitev, N and Venters, W (2009) Reflexive evaluation of an academic–industry research collaboration: can Mode 2 management research be achieved? Journal of Management Studies, 46 (5). pp. 733-754;

Munir, P, et al. (2004), ‘Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients’, BMJ, 329.;

NHS Choices. (2014). Couch to 5K.   Retrieved 26 June 2014, from http://www.nhs.uk/Livewell/c25k/Pages/couch-to-5k.aspx

Niezen, M. G., Bal, R., & De Bont, A. (2013). Reconfiguring Policy and Clinical Practice How Databases Have Transformed the Regulation of Pharmaceutical Care? Science, Technology & Human Values, 38(1), 44-66.

Nuffield Council on Bioethics. (2010). Medical Profiling and Online Medicine: The Ethics of ‘Personalised Healthcare’ in a Consumer Age. London: Nuffield Council on Bioethics.

OFT. (2007). Medicines distribution: An OFT market study. UK: Office of Fair Trading.

Olleros, X. (2008). The lean core in digital platforms. Technovation, 28(5), 266-276.

Orlikowski, W. J. (2000). Using Technology and Constituting Structures: A Practice Lens for Studying Technology in Organizations. Organization Science, 11(4), 404-428. doi: 10.2307/2640412

Petrakaki, D., Cornford, T., Hibberd, R., Lichtner, V., & Barber, N. (2011). The Role of Technology in Shaping the Professional Future of Community Pharmacists: The Case of the Electronic Prescription Service in the English National Health Service. Researching the Future in Information Systems, 356, 179-195.

Pirmohamed, M., James, S., Meakin, S., Green, C., Scott, A. K., Walley, T. J., . . . Breckenridge, A. M. (2004). Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients. Bmj, 329(7456), 15-19.

Pound, P., Britten, N., Morgan, M., Yardley, L., Pope, C., Daker-White, G., & Campbell, R. (2005). Resisting medicines: a synthesis of qualitative studies of medicine taking. Social Science & Medicine, 61(1), 133-155. doi: http://dx.doi.org/10.1016/j.socscimed.2004.11.063

PriceWaterhouseCoopers. (2007). Pharma 2020: The vision–Which path will you take: Price Waterhouse Coopers, London.

Proteus Digital Health. (2014). Digital Health Feedback System.   Retrieved 11 September 2014, from http://www.proteus.com/technology/digital-health-feedback-system/

Proteus Digital Health. (2014). Digital Medicines – Shifting the Care Paradigm.   Retrieved 11 September 2014, from http://www.proteus.com/future-products/digital-medicines/

Quah, D. (2003). Digital goods and the new economy. CEP discussion paper; CEPDP0563, 563., from http://eprints.lse.ac.uk/2236/1/Digital_Goods_and_the_New_Economy.pdf

Ren, Z., Davidian, M., George, S. L., Goldberg , R. M., Wright, F. A., Tsiatis A. , A., & Kosorok, M. R. (2014). Research methods for clinical trials in personalized medicine: a systematic review Lost In Translation: Barriers to Incentives for Translational Research in Medical Sciences. Singapore: World Scientific.

Robertson, A., Cresswell, K., Takian, A., Petrakaki, D., Crowe, S., Cornford, T., . . . Sheikh, A. (2010). Implementation and adoption of nationwide electronic health records in secondary care in England: qualitative analysis of interim results from a prospective national evaluation. British Medical Journal, 341. doi: Artn C4564

Doi 10.1136/Bmj.C4564

Schleidgen, S., Klingler, C., Bertram, T., Rogowski, W., & Marckmann, G. (2013). What is personalized medicine: sharpening a vague term based on a systematic literature review. BMC Medical Ethics, 14(1), 55.

Sheikh, A., Cornford, T., Barber, N., Avery, A., Takian, A., Lichtner, V., . . . Cresswell, K. (2011). Implementation and adoption of nationwide electronic health records in secondary care in England: final qualitative results from prospective national evaluation in “early adopter” hospitals. British Medical Journal, 343. doi: Artn D6054

Doi 10.1136/Bmj.D6054

Shi, M. M. (2002). Diagnostics meets therapeutics: the impact of pharmacogenetics ▾. Drug Discovery Today, 7(23), 1161-1162. doi: http://dx.doi.org/10.1016/S1359-6446(02)02518-7

Shoenbill, K., Fost, N., Tachinardi, U., & Mendonca, E. A. (2014). Genetic data and electronic health records: a discussion of ethical, logistical and technological considerations. Journal of the American Medical Informatics Association, 21(1), 171-180. doi: 10.1136/amiajnl-2013-001694

Singh, D. (2004). Merck withdraws arthritis drug worldwide. BMJ: British Medical Journal, 329(7470), 816.

Smith, D., & Protevi, J. (2013). Gilles Deleuze. In E. N. Zalta (Ed.), The Stanford Encyclopedia of Philosophy (Spring 2013 ed.).

Takian, A., Petrakaki, D., Cornford, T., Sheikh, A., & Barber, N. (2012).  Building a house on shifting sand: methodological considerations when evaluating the implementation and adoption of national electronic health record systems. BMC health services research, 12 (105).

Takian A, Sheikh A, Barber N. ‘Organizational learning in the implementation and adoption of national electronic health records: case studies of two hospitals participating in the National Programme for Information Technology in England’. Health Informatics Journal 2013, in press;

Tantibanchachai, C. (2014, 1 April 2014). US Regulatory Response to Thalidomide (1950-2000).   Retrieved 26 June 2014, from http://embryo.asu.edu/handle/10776/7733

Tilson, D., Lyytinen, K., & Sørensen, C. (2010). Digital Infrastructures: The Missing IS Research Agenda., vol. 21, no. 5-20th Anniversary Special Issue of Emerging Challenges. Information Systems Research, 21(5).

Toms, L., Derry, S., Moore, R. A., & McQuay, H. J. (2009). Single dose oral paracetamol (acetaminophen) with codeine for postoperative pain in adults. Cochrane Database Syst Rev(1), Art. No.: CD001547.

Vargo, S. L., & Lusch, R. F. (2004). Evolving to a new dominant logic for marketing. Journal of marketing, 68(1), 1-17.

Venters, W. and Whitley, E.A. (2012) ‘A critical review of cloud computing: researching desires and realities’ Journal of Information Technology, 27;

Welch, B. M., & Kawamoto, K. (2013). Clinical decision support for genetically guided personalized medicine: a systematic review. Journal of the American Medical Informatics Association, 20(2), 388-400. doi: 10.1136/amiajnl-2012-000892

Westbrook, J. I., Reckmann, M., Li, L., Runciman, W. B., Burke, R., Lo, C., . . . Day, R. O. (2012). Effects of two commercial electronic prescribing systems on prescribing error rates in hospital in-patients: a before and after study. PLoS medicine, 9(1), e1001164.

Wiener, N. (1954). The Human Use of Human Beings. Boston, MA: Houghton Mifflin.

Yoo, Y. (2012). Digital Materiality and the Emergence of an Evolutionary Science of the Artificial. In P. Leonardi, B. Nardi, & J. Kallinikos (Eds.), Materiality and Organizing: Social Interaction in a Technological World (pp. 134-154). Oxford: Oxford University Press.

Yoo, Y., Boland Jr, R. J., Lyytinen, K., & Majchrzak, A. (2012). Organizing for innovation in the digitized world. Organization Science, 23(5), 1398-1408.

Yoojlin, Y. (2010). Computing in everyday life: a call for research on experiential computing. MIS quarterly, 34(2), 213-231.

Zittrain, J. L. (2006). The generative internet. Harvard Law Review, 1974-2040.