mechanisms of medicines

Old drugs for new uses

Researchers at the University of Leeds are using: the anti-psychotic haloperidol; the anti-depressant fluoxetine and a local anaesthetic bupivacainein as anti-virals.

The drugs disrupt the regulation of potassium levels and this, in turn, blocks the ability of all of the group of bunyaviruses to infect cells. It’s not effective on all viruses, but is looking very promising research.

Full article here.

The development of oral anticoagulants

Nature have released a short (5 min approx.) video on the development of oral anticoagulants. It is beautifully produced and informative.

March 3rd, 2016|Medicines|0 Comments|

Medicines and assemblages

We argue that medicines are hybrids and assemblages.

Research in the placebo effect seems to support this view. In a recent article in NEJM, Kaptchuck and Miller explain:
“placebo effects are improvements in patients’ symptoms that are attributable to their participation in the therapeutic encounter, with its rituals, symbols, and interactions. … This diverse collection of signs and behaviors includes identifiable […]

On medicines: for risk markers, not factors, for disease …

… to remember to explore further:

“So much of this ‘evidence’ is for drug treatment, especially comparing one drug against another. We now have enough research evidence that shows that many of the ‘things’ doctors advise (drug) treatment for, are but markers of an underlying problem. Sadly, these are mostly for the most common of problems – risk markers, not […]

August 7th, 2014|Medicines|0 Comments|

Can ‘digital drugs’ get you high?

Can ‘digital drugs’ get you high?

Digital drugs .. as binaural beats…

Perhaps there is an ontologically purer form of DD?

February 18th, 2014|Medicine|0 Comments|