Does paracetamol do you more harm than good?

The US and UK are reviewing guidance on paracetamol (sales and prescribing) based on recent research.

““Paracetamol can actually be a very dangerous drug,” says Dr John Dickson, who retired from general practice in Northallerton, North Yorkshire, last year. “It can cause kidney and liver problems, and causes as much gastrointestinal bleeding as the NSAIDs.””


“The real problem is that the old model of judging drugs on the basis of research that averages out their effects makes little sense when these can vary dramatically between individuals. […] [for some people paracetamol provides pain relief and for others it doesn’t]. In such cases, perhaps it makes sense for patients to take a greater role in managing their own treatment, working with medical professionals to find out what works for them.”

“Now, […], Dr Martin Johnson of the RCGP says the status quo that drives GPs to prescribe prolonged use of paracetamol for millions of [chronic osteoarthritic] patients no longer makes sense.”